BPC-157 and TB-500 are often discussed together in non-clinical literature, but they are unrelated molecules with different origins, sequences and evidence bases.
| Property | BPC-157 | TB-500 |
|---|---|---|
| Class | Synthetic 15-amino-acid peptide (pentadecapeptide) | Synthetic N-terminally acetylated heptapeptide corresponding to residues 17–23 of human thymosin beta-4 |
| Molecular formula | C62H98N16O22 [1] | C38H68N10O14 [2] |
| Molecular weight (g/mol) | 1419.5 [1] | 889.0 [2] |
| CAS number | 137525-51-0 | 885340-08-9 |
| PubChem CID | 9941957 [1] | 62707662 [2] |
| Sequence | GEPPPGKPADDAGLV | Ac-LKKTETQ |
| FDA | Not approved; compounding nomination withdrawn [3][4] | Not approved; compounding nomination withdrawn [3][4] |
| Health Canada | Named among unauthorized peptide drugs seized by Health Canada [5] | Named among unauthorized peptide drugs seized by Health Canada [5] |
| WADA 2026 | Prohibited at all times, S0 Non-approved substances [6] | Prohibited at all times, S2.3 (thymosin-β4 and its derivatives) [6] |
BPC-157
BPC-157 is a synthetic 15-amino-acid peptide derived from a partial sequence of human gastric juice protein BPC. It is not FDA-approved and has no identified EMA, UK MHRA, Australian ARTG or Health Canada authorization. On its list of substances that may present significant safety risks, FDA states that it "has identified no, or only limited, safety-related information for the proposed routes of administration." [3]
Full reference: BPC-157 research reference
TB-500
TB-500 is the synthetic, N-terminally acetylated heptapeptide Ac-LKKTETQ, corresponding to residues 17–23 of human thymosin beta-4. It is not FDA-approved. FDA lists thymosin beta-4 fragment (LKKTETQ), also known as TB-500, among withdrawn compounding nominations and states that it "has not identified any human exposure data." [3][4]
Full reference: TB-500 research reference
Lot documentation
Each lot of each compound has its own Certificate of Analysis. Compare compounds only against the COA for the exact lot used.
Research use only
Ageless Peptides supplies these compounds as lyophilized material for laboratory research only. They are not drugs, foods, cosmetics or dietary supplements, are not for human or veterinary use, and nothing on this page is medical advice or a statement of safety or effectiveness for any human or veterinary use.
