Epithalon (Ala-Glu-Asp-Gly) and Pinealon (Glu-Asp-Arg) are short synthetic peptides from the same Russian research tradition and are often mentioned together. They are different molecules: Epithalon is a tetrapeptide and Pinealon is a tripeptide.
| Property | Epithalon (Epitalon) | Pinealon |
|---|---|---|
| Class | Synthetic linear tetrapeptide | Synthetic tripeptide |
| Molecular formula | C14H22N4O9 [1] | C15H26N6O8 [2] |
| Molecular weight (g/mol) | 390.35 [1] | 418.40 [2] |
| CAS number | 307297-39-8 | 175175-23-2 [2] |
| PubChem CID | 219042 [1] | 10273502 [2] |
| Sequence | Ala-Glu-Asp-Gly (AEDG) | Glu-Asp-Arg (EDR) [2] |
| FDA | Not approved; listed as "Epitalon" among withdrawn compounding nominations [3][4] | Not approved; not named on FDA's compounding safety-risk list [3] |
| Health Canada | "Epitalon" named among unauthorized peptide drugs seized by Health Canada [5] | Not named in the advisory [5] |
| WADA 2026 | Not named on the Prohibited List [6] | Not named on the Prohibited List [6] |
| Supplied by Ageless Peptides | Yes | No |
Epithalon
Epithalon, also called Epitalon or AEDG, is a synthetic linear tetrapeptide composed of Ala-Glu-Asp-Gly and derived from the pineal extract epithalamin. It is not FDA-approved. FDA lists it among substances nominated for compounding whose nomination was withdrawn, and no EMA, UK MHRA or Australian ARTG marketing authorization was identified in the reviewed evidence. [3][4]
Full reference: Epithalon research reference
Pinealon
Pinealon, also called EDR or L-glutamyl-L-aspartyl-L-arginine, is a synthetic tripeptide. It is not FDA- or EMA-approved for any indication in the reviewed evidence. Ageless Peptides does not supply Pinealon.
Lot documentation
Each lot of each compound has its own Certificate of Analysis. Compare compounds only against the COA for the exact lot used.
Research use only
Ageless Peptides supplies these compounds as lyophilized material for laboratory research only. They are not drugs, foods, cosmetics or dietary supplements, are not for human or veterinary use, and nothing on this page is medical advice or a statement of safety or effectiveness for any human or veterinary use.

