Semax and Selank are both synthetic heptapeptides that end in the same C-terminal Pro-Gly-Pro tripeptide. Semax is built on the ACTH(4-7) fragment; Selank is built on the tuftsin fragment Thr-Lys-Pro-Arg.
| Property | Semax | Selank |
|---|---|---|
| Class | Synthetic heptapeptide: ACTH(4-7) extended with C-terminal Pro-Gly-Pro [1] | Synthetic heptapeptide: tuftsin (Thr-Lys-Pro-Arg) extended with C-terminal Pro-Gly-Pro [2][3] |
| Molecular formula | C37H51N9O10S [1] | C33H57N11O9 [2] |
| Molecular weight (g/mol) | 813.9 [1] | 751.9 [2] |
| CAS number | 80714-61-0 [1] | 129954-34-3 [2] |
| FDA UNII | I5FAL2585H [1] | TS9JR8EP1G [2] |
| PubChem CID | 9811102 [1] | 11765600 [2] |
| Sequence | Met-Glu-His-Phe-Pro-Gly-Pro [1] | Thr-Lys-Pro-Arg-Pro-Gly-Pro [2] |
| FDA | Not approved; "Semax (heptapeptide)" listed among withdrawn compounding nominations [4] | Not approved; "Selank acetate (TP-7)" listed among withdrawn compounding nominations [4] |
| Health Canada | Not named in the advisory [5] | Not named in the advisory [5] |
| WADA 2026 | Not named on the Prohibited List [6] | Not named on the Prohibited List [6] |
| Supplied by Ageless Peptides | Yes | Yes |
Semax
Semax is a synthetic heptapeptide in which the ACTH(4-7) fragment, Met-Glu-His-Phe, is extended with a C-terminal Pro-Gly-Pro tripeptide. PubChem indexes it as "ACTH (4-7), Pro-Gly-Pro-". [1] It is not FDA-approved, and FDA lists it among substances nominated for compounding and subsequently withdrawn. [4]
Full reference: Semax research reference
Selank
Selank is a synthetic heptapeptide in which the tuftsin fragment, Thr-Lys-Pro-Arg, is extended with a C-terminal Pro-Gly-Pro tripeptide. [2][3] It is not FDA-approved, and FDA lists selank acetate among substances nominated for compounding and subsequently withdrawn. [4]
Full reference: Selank research reference
Lot documentation
Each lot of each compound has its own Certificate of Analysis. Compare compounds only against the COA for the exact lot used.
Research use only
Ageless Peptides supplies these compounds as lyophilized material for laboratory research only. They are not drugs, foods, cosmetics or dietary supplements, are not for human or veterinary use, and nothing on this page is medical advice or a statement of safety or effectiveness for any human or veterinary use.
